The US sanctions implemented by Trump have made the people of Iran realize their leadership needs to change.
https://foreignpolicy.com/2019/11/20/iran-protests-trump-sanctions-inflicting-serious-pain/
The deadly drama playing out in Iran since last Friday, leaving more than 100 protesters dead, shows three things. Tehran is increasingly in desperate economic straits, in part because of intense U.S. sanctions; Iranian popular discontent with the regime’s economic mismanagement seems to have reached a breaking point; and the regime is more frightened of popular unrest than at any time in recent years.
The latest explosion of popular protest in Iran began on Friday after the government rescinded fuel subsidies, which essentially tripled the price of gasoline—a painful blow to millions of ordinary Iranians already struggling to survive a debased currency, high unemployment, and a shrinking economy. But the demonstrations that began over fuel subsidies quickly became a sweeping, nationwide protest against the Iranian regime itself, with outbreaks in dozens of cities in every Iranian province, targeting especially government buildings such as police stations and state-owned banks.